Price range: $200.00 through $29,000.00
5F-MDA-19 for sale
5F MDA 19 (5 fluoropentyl MDA 19, 5 fluoro BZO POXIZID, BZO HEXOXIZID analogue) from Davechemicals.com is a high purity synthetic cannabinoid research material supplied strictly for laboratory use only, not for human or veterinary consumption. It is part of the broader MDA 19 CB2 agonist family, valued by serious researchers studying cannabinoid receptor pharmacology, analytical toxicology and seized material profiling across the United Kingdom, United States, Germany, Australia and Asia.
Buy 5F-MDA-19 Online
5F MDA 19 (5 fluoropentyl MDA 19, 5 fluoro BZO POXIZID, BZO HEXOXIZID analogue) from Davechemicals.com is a high purity synthetic cannabinoid research material supplied strictly for laboratory use only, not for human or veterinary consumption. It is part of the broader MDA 19 CB2 agonist family, valued by serious researchers studying cannabinoid receptor pharmacology, analytical toxicology and seized material profiling across the United Kingdom, United States, Germany, Australia and Asia. Buy 5F-MDA-19 Online
What is 5F MDA 19 5 fluoropentyl MDA 19 (BZO HEXOXIZID analogue) ❓
5F MDA 19, often referred to as 5 fluoropentyl MDA 19 or 5 fluoro BZO POXIZID, is a synthetic cannabinoid that belongs to the MDA 19 OXIZID family, a group of ligands designed to interact primarily with cannabinoid receptors, especially CB2. The parent compound MDA 19 (BZO HEXOXIZID) was initially explored as a CB2 selective agonist for neuropathic pain research, with data showing potent binding at CB2 and relatively lower affinity for CB1 compared with earlier synthetic cannabinoids.
According to open literature and forensic reports, 5F MDA 19 is the 5 fluoropentyl analogue of MDA 19, identified in synthetic smoke blends and seized materials as part of the newer OXIZID generation of cannabinoids. Databases and monographs from groups such as the Center for Forensic Science Research and Education and international bodies like UNODC describe 5F BZO POXIZID as an MDA 19 analogue with a fluorinated pentyl side chain, detected in real world casework from 2021 onwards.
All 5F MDA 19 materials offered on the Davechemicals.com are supplied strictly for research purposes, not for human use, ingestion or any form of in vivo administration.
Why 5F MDA 19 CB2 agonist research matters for serious labs
The original MDA 19 CB2 agonist was studied for neuropathic pain models because CB2 biased ligands can modulate inflammatory and immune related pathways with potentially reduced classic CB1 psychoactivity in animals, although translation to humans is not straightforward. A recent pharmacological evaluation of newer OXIZID synthetic cannabinoids found that MDA 19 produced partial CB1 and CB2 receptor activation in vitro, with an activity profile that resembled THC at certain doses, yet also showed strong rate suppression and variable behavioural effects at higher doses in animals.
For forensic and analytical labs in the UK, USA, Germany, Australia and Asia, 5F MDA 19 and related analogues present three main challenges.
- Identification in seized herbal blends and liquids.
- Limited historic toxicological data, which increases uncertainty.
- Rapid emergence of multiple MDA 19 analogues, including pentyl, 5 fluoropentyl and cyclohexylmethyl versions.
Because of that, many laboratories now build targeted LC MS and GC MS methods around MDA 19 and 5F MDA 19 reference standards, often alongside other cannabinoids sourced from specialist vendors such as Cayman Chemical and informed by NPS monitoring projects and open references.
5F MDA 19 5 fluoropentyl MDA 19 structure and pharmacology
Sources such as Wikipedia and NPS alerts describe MDA 19 and its 5 fluoropentyl analogue as indolinone based synthetic cannabinoids that bind to CB1 and CB2 receptors. The 5 fluoropentyl chain in 5F MDA 19 is structurally analogous to the fluorinated side chains found in earlier synthetic cannabinoids, a modification that has often increased potency at CB1 and CB2 receptors and raised concern in toxicology.
Key points taken from public data on the MDA 19 family.
- MDA 19 shows Ki values in the low nanomolar range at human CB2 receptors and somewhat weaker affinity at CB1, with species differences between rat and human receptors.
- MDA 19 behaves as a CB1 and CB2 agonist in humans, while acting as an inverse agonist at rat CB2 receptors, which underlines how preclinical species data can be misleading if assumed to translate directly.
- 5F analogues such as 5F MDA 19 5 fluoropentyl MDA 19 are flagged by forensic groups as “new generation synthetic cannabinoids”, associated with psychoactive effects and adverse events when used outside controlled research environments.
According to a recent paper on OXIZID cannabinoids, MDA 19 at higher doses in mice caused strong reductions in response rates and variable behaviour, highlighting that “CB2 selectivity” in binding studies does not automatically mean a gentle or predictable clinical profile.
Buy 5F MDA 19 online for laboratory research only
At Davechemicals.com, our buy 5F MDA 19 online listing is aimed at accredited laboratories and experienced researchers who need a consistent 5F MDA 19 (5 fluoropentyl MDA 19) reference standard.
The product is clearly labelled as for research purposes only and shipped only to verified institutional or professional clients, not to casual buyers or individuals seeking personal use.
Our 5F MDA 19 offer is positioned alongside other synthetic cannabinoids such as 5F MDMB, 5F SGT 151, JWH 122 , JWH 210 cannabinoid and EG 018, giving forensic and toxicology teams the option to build a broad cannabinoid panel from a single supplier.
Researchers who also work across dissociatives, stimulants and tryptamines can expand their catalogue with materials like buy 3 MeO PCP online, buy 2 FDCK online USA, buy 5 MeO DMT online or more classical entactogens such as methylone, again strictly for research.
If you need tailored support, batch documentation or region specific shipping advice, you can contact the team via the Davechemicals.com contact to discuss 5F MDA 19 availability for the UK, USA, Germany, Australia or Asia.
Table 1, 5F MDA 19 vs parent MDA 19 vs 5F MDMB 2201
Profile overview of key synthetic cannabinoids for research
| Feature | 5F MDA 19 (5F BZO POXIZID) | MDA 19 (BZO HEXOXIZID) | 5F MDMB 2201 |
|---|---|---|---|
| Core scaffold | Indolinone OXIZID family | Indolinone OXIZID family | Indazole 3 carboxamide |
| Side chain | 5 fluoropentyl | Hexyl | 5 fluoropentyl tert leucinate |
| Intended target in early research | CB2 biased agonist analogue | CB2 selective agonist, neuropathic pain models | Potent CB1 CB2 agonist in early synthetic cannabinoid waves |
| Detection context | Identified in synthetic smoke blends and seized samples | Identified in seized synthetic blends and research lists | Widely detected in NPS casework and toxicology |
| Expected risk if misused | High, limited human data, potential for severe adverse effects | High, psychoactive potential despite CB2 focus | Very high, associated with serious intoxications |
| Research use | Reference standard for analytical methods, receptor and metabolism work | CB2 pharmacology, SAR, analytical standards | Toxicology, seizure profiling, method validation |
These materials are not approved medicines and should never be treated as safe alternatives to regulated therapeutics.
How 5F MDA 19 5 fluoropentyl MDA 19 is classified and controlled
International bodies including UNODC list 5F MDA 19 5 fluoropentyl MDA 19 under the systematic naming for MDA 19 analogues, highlighting its role as a new generation synthetic cannabinoid of concern.[4][3] Many jurisdictions, particularly in Europe, North America and parts of Asia, now control such substances through generic synthetic cannabinoid legislation or analogue laws, which means 5F MDA 19 can fall under controlled substance frameworks even if not named explicitly.
According to public legal response summaries for these analogues, the trend is clear, lawmakers respond quickly to newly detected cannabinoids, especially those linked to intoxication clusters, and forensic labs are expected to keep up with rapidly shifting schedules. Researchers planning to buy 5F MDA 19 online must therefore check local regulations, institutional policies and any licence requirements long before placing an order, because ignorance of the exact wording of a schedule does not hold up when authorities review seized materials.
Table 2, Analytical handling of 5F MDA 19 in the laboratory
Practical research considerations for 5F MDA 19
| Aspect | Laboratory guidance for 5F MDA 19 | Notes |
|---|---|---|
| Sample form | Typically supplied as solid powder, sealed, labelled for research only | Store in airtight containers away from light and moisture. |
| Recommended use | Analytical reference, method validation, in vitro receptor or metabolism work | No in vivo or human self administration, regardless of anecdotal reports. |
| Instrument platforms | LC MS MS, GC MS and HRMS for seized material screening | Many labs build compound libraries based on CFSRE and UNODC alerts. |
| Documentation | COA, purity data, batch identifiers, safety datasheet | Reputable suppliers and reference vendors provide full documentation. |
| Handling risk | High risk if mishandled, unknown human toxicology, potential for severe CNS effects | Follow strict PPE, fume hood work and controlled access policies. |
| Co standards | Often used alongside JWH series, 5F MDMB 2201, ADB FUBINACA, SGT 25 and others | Helps build robust panels for emerging synthetic cannabinoid detection. |
Handling practices should follow internal hazardous substance policies and international occupational safety guidance, with explicit written procedures for synthetic cannabinoids
Other cannabinoids and research chemicals that pair with 5F MDA 19
Serious laboratories rarely work with 5F MDA 19 in isolation, they typically build panels that cover both legacy and next generation materials.
Within Davechemicals.com , 5F MDA 19 can sit alongside:
- buy 5F UR144 online for earlier indole based synthetic cannabinoid profiling.
- buy AMB PINACA online and 4F ADB for indazole carboxamide coverage.
- AM 2201 and SGT 25 to capture high potency CB1 biased ligands.
- ADBB powder and buy 6CL ADB A online for additional OXIZID and indazole analogues.
Labs with broader NPS responsibilities might also stock dissociatives such as deoxymethoxetamine, cathinones like 3 MMC, and entactogens such as methallylescaline or proscaline, depending on local law and the profile of seized materials they see.
Table 3, Selecting a supplier for 5F MDA 19 and related standards
What serious labs look for when they buy 5F MDA 19
| Criterion | Why it matters for 5F MDA 19 | How Davechemicals.com responds |
|---|---|---|
| Clear “research only” positioning | Synthetic cannabinoids such as 5F MDA 19 are not safe consumer products, they belong in controlled labs only | Every listing, including 5F MDA 19, is marked not for human consumption. |
| Documentation quality | CB2 OXIZID ligands need traceable purity, batch codes and SDS for legal and scientific reasons | We provide COA, batch data and safety sheets with each shipment where applicable. |
| Geographic experience | Laws differ across the UK, USA, Germany, Australia and Asia, and mis shipments can be costly | Our team has long experience shipping research chemicals into these regions within legal frameworks. |
| Product breadth | Synthetic cannabinoid panels are only useful when they cover multiple structural classes | Our catalogue includes 5F MDA 19, legacy JWH series, SGT compounds, and many non cannabinoid NPS. |
| Straight communication | Labs need honest replies on legality, availability and risk, not marketing spin | We are blunt about what we supply, what we refuse, and why, via Davechemicals.com contact. |
Safety, ethics and straight talk on 5F MDA 19
Databases such as DrugBank and Drugs.com focus on approved or clinically relevant substances, which already shows the gap between legitimate medicine and experimental synthetic cannabinoids like 5F MDA 19.[1][5] Platforms that discuss non medical use, including PsychonautWiki and TripSitter, routinely point out that novel cannabinoids come with unpredictable toxicity, limited dose response data and a history of severe incidents, including hospitalisation and death.
From a research perspective, this translates into a few blunt truths.
- 5F MDA 19 is not a “safer weed”, it is an experimental ligand with poorly characterised risk in humans.
- Any non laboratory use is reckless, especially given known problems with previous synthetic cannabinoids.
- Ethical research requires clear protocols, documented approvals and strict separation between analytical work and any idea of “recreational” consumption.
For that reason, Davechemicals.com does not market 5F MDA 19 or related substances as lifestyle products, only as research chemicals for professionals who know exactly what they are dealing with.
What is 5F MDA 19 5 fluoropentyl MDA 19 used for in research?
Researchers use 5F MDA 19 5 fluoropentyl MDA 19 as a synthetic cannabinoid reference standard for analytical toxicology, receptor binding work and metabolism studies, particularly in the context of emerging NPS detection. It helps laboratories confirm the presence of MDA 19 analogues in seized products and to understand how these substances behave in experimental systems, not as candidates for consumer use.
Is 5F MDA 19 legal in the UK, USA, Germany, Australia or Asia
Legal status of 5F MDA 19 is complicated and varies between jurisdictions, with many countries using generic or analogue laws that capture synthetic cannabinoids even when individual names are not listed. According to public alerts and UNODC data, MDA 19 analogues, including 5F structures, are increasingly treated as controlled substances, so only compliant institutions with proper licences should handle them
How strong is 5F MDA 19 compared with other synthetic cannabinoids?
While specific human potency data for 5F MDA 19 are limited, the parent MDA 19 has shown CB2 receptor affinities in the low nanomolar range and partial agonist profiles similar in some respects to THC, which indicates significant activity at cannabinoid receptors. Forensic documents warn that 5F analogues of established cannabinoids often display high potency and have been linked with serious adverse events, so 5F MDA 19 should be treated as a high risk compound in any non research context.
Can 5F MDA 19 be used as a medicine or “legal high”
There is no regulatory approval for 5F MDA 19 as a medicine, and current data focus on preclinical and forensic aspects rather than human therapeutic use.[5][3][1] Synthetic cannabinoids of this type have been implicated in severe intoxications and fatalities, so promoting them as “legal highs” is irresponsible, inaccurate and completely at odds with the way reputable sources, including UNODC and forensic alerts, describe them.
Where can qualified labs buy 5F MDA 19 online safely?
Qualified laboratories can obtain 5F MDA 19 from specialist research chemical suppliers that provide full documentation, clearly mark products as not for human consumption and have a track record with NPS reference standards. We offer 5F MDA 19 through the buy 5F MDA 19 product page on Davechemicals.com, alongside related synthetic cannabinoids like buy SGT 280 online and buy 5F PCN online, with shipping focused on verified institutions in the UK, USA, Germany, Australia and Asia.
How does 5F MDA 19 compare with classic cannabinoids like THC?
MDA 19 has shown a partial agonist profile at CB1 and CB2 receptors that, according to one study, produced behavioural effects reminiscent of THC at certain dose ranges while also causing marked rate suppression at higher doses. However, 5F MDA 19 is a structurally modified analogue, and forensic alerts underline that potency and toxicity can exceed that of THC by a wide margin, especially when uncontrolled material is smoked or ingested.
What precautions should labs take when handling 5F MDA 19?
Labs should treat 5F MDA 19 as a potent psychoactive substance with unknown human safety margins, enforce strict PPE, use fume hoods and ensure only trained staff handle open material. All handling should follow hazardous drug procedures, with secure storage, accurate logs, and clear separation between analytical spaces and any area accessible to non technical staff.
Are there metabolism or biomarker data for MDA 19 analogues
Preclinical metabolism data for MDA 19 and related analogues have started to emerge in forensic and pharmacology literature, often in the context of identifying urinary metabolites and mass spectral fragments for toxicology panels. For now, labs mainly rely on reference spectra, case reports, and in vitro metabolism work to build screening methods, which makes access to well characterised 5F MDA 19 standards particularly valuable.
Why do some synthetic cannabinoids target CB2?
CB2 biased ligands like MDA 19 were initially attractive because CB2 is associated with immune and inflammatory pathways, which raised the idea of analgesia or anti inflammatory effects with reduced classic CB1 side effects. However, research over the past decade shows that the relationship between receptor selectivity and clinical risk is far more complicated, and many supposedly “CB2 selective” compounds still present serious safety issues.
How does 5F MDA 19 fit into the broader NPS landscape?
According to NPS monitoring programmes and forensic alerts, MDA 19 and its analogues are part of a newer wave of OXIZID synthetic cannabinoids that accompany indazole and indole carboxamides in seized herbal products. For labs that want an honest picture of what is happening on the ground, adding 5F MDA 19, SGT series cannabinoids, JWH analogues, and key dissociative and stimulant standards helps ensure that analytical panels genuinely match the substances appearing in casework.
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